Characterization of a human cell line stably over-expressing the candidate oncogene, dual specificity phosphatase 12.
Analysis of chromosomal rearrangements within primary tumors has been influential in the identification of novel oncogenes.Identification of the "driver" gene(s) within cancer-derived amplicons is, however, hampered by the fact that most amplicons contain many gene products.Amplification of 1q21-1q23 is strongly associated with liposarcomas and mic